Intraumblical Infusion of Oxytocin; As an Efficacious Route for Prevention of Complications of 3rd Stage of Labor at Tertiary Care Hospital of Sindh

  • Farhana Anjum Associate Professor, Dept. of Obs & Gynae, Isra University Hospital Hyderabad
  • Roomi Memon Senior Lecturer, Physiology department Isra University Hospital, Hyderabad
  • Farah Naz Department of OBS and Gynae, Liaquat University Hospital Hyderabad
  • Samreen Pathani Assistant Professor, Pharmacology department, Isra University Hospital Hyderabad
  • Farzana Memon Senior Lecturer, Physiology department, Isra University Hospital, Hyderabad
  • Mozna Talpur Assistant Professor, Pharmacology department, Isra University Hospital Hyderabad.
Keywords: Intraumblical oxytocinnon, 3rd stage of labo, maternal morbidity


Objective: To determine the efficacy of intraumblical oxytocin with intravenous oxytocin to reduce the 3rd stage labor related complications.
Methodology: This case control study was conducted on 100 parturient women at LUMHS University Hospital Hyderabad Sindh in a period of 1 year from February 2016 to January 2017. All the patients with reproductive age having singleton pregnancy with cephalic presentation undergoing uncomplicated labor reaching 3rd stage of labour with no medical and obstetrical complication were randomly recruited into two groups. Group 1 given 10 units of oxytocin with 20ml of normal saline through intraumblical vein infusion by (Pipangas technique) for the 3rd stage of labor management. While in Group 2 (control group) were given 10 unit of oxytocin on intravenously for 3rd stage labor management. In both groups the duration of 3rd stage in minutes, amount of blood loss in milliliters and complications were documented. Data was recorded in the preform and analyzed by spss version 16.
Results: Hundered patients were studied, 50 in study group A and 50 in group B (control). Most of the patients were with age group of 21-30 years 30(60.0%) in study group and 25(50.0%) in control group, p-value 0.041. Blood loss was markedly decreased in study group in contrast to controls, p-value 0.001. Third stage labor markedly decreased in study group 4.57±3.29 minutes as compared to control group 8.19±4.2 minute, p-value 0.0005. Complications were less in study group, while statistically insignificant, p-value 0.426.
Conclusion: Intraumblical oxytocin with intravenous oxytocin showed the best effectiveness in 3rd stage related blood loss and labor duration with fewer complications. 

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