Frequency of Molar Pregnancy in Patients Presenting With Miscarriage

Abstract

Background: The present study aimed to determine the frequency of molar pregnancy in patients presenting with miscarriage.

Methods: A descriptive cross-sectional study was undertaken at the outpatients Department of Obstetrics & Gynaecology, JPMC, Karachi, Pakistan between September 25, 2020 to March 24, 2021. All patients who fulfilled the inclusion criteria and visited JPMC, Karachi were included in the study. Informed consent was taken after explaining the procedure, risks and benefits of the study. Data regarding age, gestational age and parity was obtained and noted. Transabdominal ultrasound scanning was done to assess the molar pregnancy. All the collected data were entered into the proforma attached at the end and used electronically for research purposes.

Results: A total of 178 patients were included with a mean age of 28.7 ± 5.8 years. A mean parity of 2.4 ± 0.95 and a gestational age of 11.2 ± 3.5 weeks were observed. Previous molar pregnancy was found in 65 (36.5%) patients and a positive family history of molar pregnancy was found in 33 (18.5%) patients Molar pregnancy was found to be in only 01 (0.5%) patient. No significant association was found between age, BMI, parity, gestational age, previous molar pregnancy, and family history.

Conclusion: It is to be concluded that molar pregnancy is very less likely prevalent in patients with miscarriage, but we cannot rule out residual confounders.

Keywords: Histopathology, Hydatidiform, Miscarriage, Molar Pregnancy, Mole, Placenta, Ultrasound