The Relation of Metabolic Markers with Serum Insulin in Women with Polycystic Ovary Syndrome

Abstract

Objective: Polycystic ovarian syndrome (PCOS) is a serious endocrinopathy that affects a large number of women during their reproductive years, although it is often underappreciated as a major health problem globally. The current study intends to investigate the relationship between metabolic indicators and blood insulin levels in women with polycystic ovarian syndrome

Methodology: A cross-sectional study was carried out in the obstetrics/gynecology department with the help of the Department of Physiology at LUMHS Jamshoro, data was collected from patients visited the OPD at LUMHS Jamshoro/Hyderabad.

Results: The mean levels of serum insulin among premenopausal diabetic women with normal weight was 27.6±2.27MiU/L, where as in over weight females the levels were 31.45±2.71MiU/L. Among obese female the mean levels of serum insulin were raised to 34.72±3.65MiU/L, hence revealing that increase BMI is associated with increased levels of serum insulin.  Further to determine the association between increase Body Mass Index and Serum insulin level Pearson regression test was applied that suggested non-significant correlation (Multiple R=0.108, R Square = 0.011, p=0.45) between the two variables

Conclusion: The findings of a study examining the relationship serum insulin levels in women with PCOS, blood insulin levels differed significantly between individuals with normal BMI and those who were overweight or obese, but there was no linear relationship between BMI and insulin levels.