The Most Common Phenotype of Polycystic Ovary Syndrome in Women Attending Outpatient Department of Tertiary Care Hospital

Misbah Mahmood; Yasmeen Nawaz Khooharo; Madho Bala Sharma; Nazli Hussain; Bushra Asif; Hira Hanif

Misbah Mahmood Senior Registrar, Gynae and OBS, Muhammad Medical College Mirpur Khas
Yasmeen Nawaz Khooharo Professor, Gynae and OBS, Muhammad Medical College Mirpur Khas
Madho Bala Sharma Assistant Professor, Gynae and Obs, Muhammad Medical College Mirpur Khas
Nazli Hussain Professor, Gynae and Obs, DHU Civil Hospital, Karachi
Bushra Asif Senior Registrar, Gynae and OBS, Muhammad Medical College Mirpur Khas
Hira Hanif Senior Registrar, Gynae and OBS, Muhammad Medical College Mirpur Khas

Keywords: Polycystic Ovarian syndrome, oligomenorrhea, amenorrhea, anovulation

Abstract

Objective: To determine the phenotype of polycystic ovary syndrome in women attending the outpatient department of tertiary Care Hospital
Settings: Outpatient Department of Civil Hospital Karachi.
Methodology: This descriptive case series study was conducted at the Outpatient Department of Civil Hospital Karachi from 1/1/2017 to 30/6/1218. All reproductive age women between 14 and 45 years of age who complained of hirsutism, acne, hair loss, infertility, menstrual irregularity & weight gain were included. Each subject was asked to provide a detailed menstrual history, and data were collected for each subject on body, weight, height were measured and BMI was calculated. The patient venous blood was drawn for serum prolactin, progesterone, serum Testosterone dehydroepiandrosterone sulfate, sex hormone binding globulin was sent. All the information was evaluated by enclosed proforma by the researcher. The collected data was analyzed by using SPSS Version 26.
Results: The average age of the women was 26.16±6.33 years. Most of the women were nulliparous 54.0%, followed by 41.14% were multiparous and 24.86% were primiparous. One hundred and sixty-six (47.43%) were obese. As per the phenotype of polycystic ovary syndrome in women as oligomenorrhea, amenorrhea, anovulation, weight Loss, clinical hyperandrogenism, hirsutism acne, androgenic alopecia (Hair Loss) and biochemical Hyperandrogenism among patients of 52.6% 60.3%, 52.0%, 58.9%, 74.3%, 58.6%, 45.1%, 43.4% and 66.0% respectively. Phenotype of polycystic ovary syndrome was observed to be statistically significant with respect to age and obesity (p-<0.05).
Conclusion: Oligomenorrhea, amenorrhea, anovulation, weight loss, clinical hyperandrogenism, hirsutism acne, androgenic alopecia (Hair loss) and biochemical hyperandrogenism observed to be the commonest phenotypes of polycystic ovarian syndrome. Polycystic ovarian syndrome, a common problem of women of the reproductive age group is affecting their life physically, mentally and socially.