Impact of Deranged Oral Glucose Tolerance Test (OGTT) On Perinatal Outcomes

Abstract

Objective: To assess the frequency of adverse perinatal outcomes in patients with deranged Oral Glucose Tolerance Test (OGTT) results

Methodology: This study was conducted from 1st January 2021 to 1st January 2022 in the Outpatient Department (OPD) of our tertiary care hospital. One hundred and seventy-five pregnant women fulfilling the inclusion criteria of the study were selected from outpatient clinics. Demographic data of study participants were recorded on the devised proforma and based on OGTT results the participants were divided into two groups. Perinatal outcomes were compared between the groups. The distribution showed a normal reshaped curve hence paired sample student t-test was used to study the results. P value was calculated to assess the significance of the difference seen between groups.

Results: Among these 200 patients 140 had normal OGTT (group 1) results while 35 had deranged OGTT (group 2). Mean parity was 1.70 +/- 0.453, in group 1 and 1.80 +/- 0.406, Booking Body mass index (BMI) in group 1 was 1.85 +/- 0.641 while in group 2 was 2.28 +/- 0.621. BMI at the time of booking was statistically greater in women with the deranged OGTT group. Group 1 had a significantly lower incidence of previous GDM 1.57+/-0.502 in comparison to group 2 where the mean value was 1.95 +/- 0.2The mean gestational age at delivery was 38.5 +/- 1.02 in group 1 and 38.1 +/-0.993 in group 2. Neonatal birth weights varied significantly between groups with babies es with h greater mean birth weight of 2.1 +/- 0.663 in-group 2 and a lower mean neonatal weight of 1.9 +/- 0.467 in patients group 1.

Conclusion: Increased BMI is associated with deranged OGTT which in turn results in poor perinatal outcomes.