Thrombocytopenia In Pregnancy; Characteristic, Risk Factors and Outcomes
Abstract
Objective: To evaluate the clinical characteristics, risk factors of thrombocytopenia and its possible outcomes during pregnancy and after delivery.
Methodology: This cross sectional study was conducted in Ghulam Medical college Sukkur October 2020 to march 2021. Thirty five pregnant women with platelet count less than 150,000/uL were enrolled in study after informed consent self-structured proforma used and patient was followed till delivery and maternal and fetal outcome observed.
Results: The most common cause of thrombocytopenia was gestational thrombocytopenia (37.1%), followed by pre- eclampsia (17.1%) and idiopathic thrombocytopenia (14.3%). Thrombocytopenia was significantly linked to the adverse feto-maternal outcome (p=<0.05). The major maternal complication was APH 8.6%, 5.7% PPH, 25.7% admitted in ICU and mortality 2.9%, while major fetal adverse outcomes pre-term births and neonatal sepsis, while mortality was 2.9%.
Conclusion: In the study conclusion, the thrombocytopenia in pregnancy was observed to be the major cause of the adverse feto-maternal outcome. Bleeding per vagina and gums, bleeding from nose, anemia and jaundice were seems to be the commonest characteristics, while gestational thrombocytopenia, pre-eclampsia, idiopathic thrombocytopenia and DIC were observed to be the commonest causative factors
Keywords: thrombocytopenia, gestational thrombocytopenia, risk factors, outcome
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