Outcome of Radical Hysterectomy with Nodal Dissection in Endometrial Tumors

Abstract

Objective: To find out the effect of lymph node dissection in early stage endometrial cancer on the overall survival and morbidity and to study effect of lymph node dissection on the post-operative adjuvant therapy.

Methodology: This was a retrospective analysis of data from the gynecological oncology registries collected at Gynaecology department, PIMS Hospital, Islamabad, from January 2022 to December 2022. Data was collected from the gynecological oncology registries collected at Gynaecology department, PIMS Hospital, Islamabad, over a span of 1 year from January 2022 to December, 2022.  A total of 48 patients presented with endometrial cancer, of them 22 were early stage and 6 patients were selected and undergone radical hysterectomy along with pelvic lymph node dissection (LND). Every procedure was carried out by a team of senior consultants in liaison with the surgery department. Administrative permission to retrieve data was taken from the head of department. Ethical permission was taken from patients/guardians at the time of surgical procedure.

Results: The patient age ranged from 40 to 60 years and had no associated co-morbidities. Females belong mostly to the younger age groups and regain a good quality of life easily postoperatively. Of the total, 6 (12.5%) had undergone LND. There were 3 (6.2%) patients had positive nodes and required adjuvant treatments. There were 2 (4.1%) patients who had negative nodes while 1 (2.0%) had reactive nodes but they were negative for malignancy. Out of total 48 cases, 14 (29.1%) patients had wound infection as an immediate complication while of the 6 patients undergone additional LND, 1 (16.6%) had wound infection.

Conclusion: Radical hysterectomy with pelvic lymph node dissection for early stage endometrial cancer has a better patient outcome.