Thrombotic Thrombocytopenic Purpura(TTP) In Pregnant Patient

Musserat  Ashraf; Aiza Khalid; Samina   Amanat; Masooma  Raza; Tariq  Hussain

doi:10.71104/jsogp.v14i4.838

Musserat Ashraf Consultant obstetrician and Gynaecologist, Department of Obstetrics and Gynecology, PAEC General Hospital, Islamabad
Aiza Khalid Postgraduate trainee gynae, Department of Obstetrics and Gynecology, PAEC General Hospital, Islamabad
Samina Amanat Consultant Hematologist, Department of Haematology, Samina Amanat Lab & Medical Center, Rawalpindi
Masooma Raza Principal medical Officer, Department of Pathology, PAEC General Hospital, Islamabad
Tariq Hussain Consultant Physician Department of Medicine, PAEC General Hospital, Islamabad

DOI: https://doi.org/10.71104/jsogp.v14i4.838

Keywords: Plasma Transfusion, Thrombotic thrombocytopenic purpura

Abstract

A 22 years old primigravida presented with loose motion, fever and atonic seizures at home. Patient was markedly pale and dehydrated. Her blood pressure was 110/70 mmHg, temp 100F and pulse 100/min. On obstetric examination baby was corresponding to dates and liquor was adequate. Her complete blood count and serum electrolytes were done. Platelet count was only 16,000/uL. Patient was admitted for evaluation and management. Urgent hematological and medical consultation was done and diagnosis of Thrombotic thrombocytopenic purpura was made. Patient was put on steroids and daily plasma transfusion. Her platelet count improved dramatically and pregnancy was taken to 35 weeks of gestation and baby delivered by cesarean section.