Biochemical Analysis and Frequency of Vitamin D Deficient People in Different Age and Gender

  • Dr Jamila 1Associate Hematologist Islamabad diagnostic Centre. Associate Professor Pathology Wah Medical College
  • Rizwan Ahmed Kiani Department of Biochemistry and Biotechnology, PMAS Arid Agriculture University, Rawalpindi.
Keywords: Vitamin D, Sun light, Phosphorus

Abstract

Biochemical Analysis and Frequency of Vitamin D Deficient People in  Different Age and Gender

Objective: To analyze different biochemical Parameters in Vitamin D deficient population and to estimate prevalence of vitamin D deficiency in different age and gender.

Methodology: This cross sectional study was conducted at Islamabad Diagnostic Centre (IDC), Islamabad from January 2017 to March 2018. In this study a total of 721 participants were recruited. Vitamin D3, total calcium, phosphorus, urea, creatinine and uric acid were analyzed on Architect 1000. Statistical analysis was analyzed by SPSS version 19.0.

Results: Out of 721 recruited patients, there were 374 (51.8%) male and 347 (48%) were female. The mean values of vitamin D, total calcium, phosphorus, urea, creatinine and uric acid were 23.4 ng/ml (± 18.40 SD), 9.1 mg/dl (± 0.66 SD), 3.4 mg/dl (± 0.60 SD), 30.2 mg/dl (± 1.4 SD), 0.94 mg/dl (± 0.68 SD) and 5.6 mg/dl (± 1.5 SD) respectively. The overall vitamin D deficiency (Deficient + Insufficient) was seen in 558 (77.4%) study participants while 160 (22.1%) participants having sufficient level. Vitamin D toxicity was seen in only 03 (0.41) patients. It was observed that there is statistical significant difference (p<0.05) in the mean value of all parameters.

Conclusion: Vitamin D deficiency in Pakistan is becoming endemic and it is much predominant in elder and female population. Female are more deficient due to social and religious limitations. They need more care of vitamin D blood levels due to less exposure to sun light in cities. Based on our finding renal function tests, serum calcium and phosphorus levels are not the conjecturer of vitamin D deficiency.

Published
2019-02-08
Section
Original Articles