False Positive 1 Hour Glucose Challenge Test and Adverse Obstetric and Perinatal Outcomes

  • Ifat Baloch Assistant Professor, Department of Obstetrics & Gynaecology, Bilawal Medical College, Jamshoro, Kotri
  • Rani Mukesh WMO, Department of Obstetrics/Gynaecology, Liaquat University of Medical and Health Sciences Jamshoro, Hyderabad
  • Naseem Bajari Research associate, Department of research Centre LUMHS Jamshoro, Hyderabad
  • Sabreena Talpur Research Associate Assistant, Department of Obstetrics/Gynaecology, Liaquat University of Medical and Health Sciences4Research Associate Assistant, Department of Obstetrics/Gynaecology, Liaquat University of Medical and Health Sciences
Keywords: Gestational diabetes mellitus, Glucose challenge test, perinatal outcome

Abstract

Objective: To determine the adverse obstetrics and perinatal outcome in false positive glucose challenge test group and negative glucose challenge test group.

Methodology: This cross sectional descriptive was conducted at department of Obstetrics and Gynecology Liaquat University of Medical and health Science Study duration was six months from March 2016 to August 2016. All the pregnant women with 28 to 42 weeks of gestational age maternal >18 years were included. All the women were divided in two groups as 50 with false +ve glucose challenge test and 50 pregnant women with –ve glucose challenge test. Results of glucose challenge test were confirmed by OGTT. Data regarding false positive GCT as a significant independent risk factor for an adverse obstetric and perinatal outcome was entered in the proforma.

Results: On average, the patients in false positive GCT study group were older, of higher parity, and more frequently had chronic hypertension and high body mass index. This group had higher mean birth weight and higher caesarean delivery and shoulder dystocia rates. The group also had higher rates of preterm delivery, severe pre-eclampsia and PPROM. After controlling for all confounding variables and effect modification we determined that a false positive GCT was significant independent risk factor for an adverse obstetric and perinatal outcome.

Conclusion: In conclusion, patients who had false positive GCT were at high risk for perinatal complications when compared to GCT negative patients.

Published
2019-05-02
Section
Original Articles