Frequency of Vitamin D Deficiency in Women with Polycystic Ovarian Syndrome

  • Rabia Jameel Department of Obstetrics & Gynaecology, Dow University of Health Sciences, Karachi
  • Arooj Kamran Dept of Obstetric & Gynecologist Dow University of Health Sciences, Karachi
  • Samar Abbas Jaffri Assistant Professor of Medicine, Liaquat National Hospital and Medical College, Karachi
  • Sadia Sultan Laboratory Services, Consultant Hematologist, National Medical Centre, Karachi
Keywords: Vitamin D deficiency, Polycystic ovary syndrome


Objective: To determine the frequency of vitamin D deficiency in women with the polycystic ovarian syndrome.
Methodology: This descriptive cross sectional study was conducted in Department of obstetrics and gynecology, civil hospital Karachi from July 18, 2014 to Jan 18, 2015. A total of 93 patients with PCOS were included in this study. Vitamin D deficiency was considered as 25-hydroxyvitamin D [25OHD] level < 20 ng/ml. Pregnant women with pre-existing medical conditions like hypertension, diabetes mellitus, acute pelvic inflammatory disease, liver or renal diseases, fibroid, and malignancies were excluded for this study.
Results:  The mean age, duration of PCOS and BMI of the study population was 34.1 ± 4.6 years, 2.5 + 1.2 years and 20 + 3.0 kg/m2 respectively. Out of the 93 patients, 35(37%) had no parity, 36(39%) had single parity, 15(16%) had two parity and 07 (08%) had more than two parity. A total of 61(65%) of women with PCOS had vitamin D deficiency.
Conclusion:  As our study shows the prevalence of vitamin D deficiency among women with PCOS is substantial. Although our findings suggest that the role of vitamin D in the pathogenesis of PCOS is not yet clear, vitamin D deficiency is a common finding among PCOS patients. Finally, the potential relationship between vitamin D and PCOS requires further investigation.

Original Articles