Diagnostic Accuracy of Transvaginal Ultrasonography for Detection of Endometrial Carcinoma with Post-Menopausal Bleeding Taking Histopathology as Gold Standard

  • Hina Zafar Department of Obstetrics and Gynaecology, Lady Aitchison hospital, Lahore
  • Saleha Ijaz Department of Obstetrics and Gynaecology, Lady Aitchison hospital, Lahore
  • Maryam Hussain Department of Obstetrics and Gynaecology, Lady Aitchison hospital, Lahore
  • Hafsa Kafayat Department of Obstetrics and Gynaecology, Lady Aitchison hospital, Lahore
  • Sadaf Mubeen Department of Obstetrics and Gynaecology, Lady Aitchison hospital, Lahore
Keywords: Transvaginal Ultrasonography, Post-Menopausal Bleeding, Histopathology, Endometrial Thickness, Endometrial Carcinoma

Abstract

Objective:To determine the diagnostic accuracy of transvaginal ultrasonography for endometrial carcinoma among women presented with menopausal bleeding.
Methodology: This cross sectional study took place at Obstetrics and Gynaecology Department of Lady Aitchison Hospital, Lahore. All females underwent TVS for assessments of endometrial thickness were included. Endometrial cavity examination was done from (internal os to fundus) in both the coronal and the saggital planes. Biopsy specimens were taken by D&C and sent to Hospital pathology laboratory for histopathology and findings were compared with TVS. All this information was recorded on proforma. Data analysis was done using SPSS 20.
Results: The patients’ mean age was 67.82±7.98 years. Mean duration of menopause was 11.55±7.74 years. Mean endometrial thickness on TVS was 5.56±3.27mm. 67% females had Endometrial thickness <4mm on TVS showing endometrial cancer as positive while 92 (33%) were negative. There were 185 (66%) females who had endometrial cancer as positive on histopathology while 92 (33%) were negative on histopathology. The sensitivity, specificity, NPV, PPV and diagnostic precision for TVS were calculated as 95.1%, 87.4%, 90.2%, 93.6% and 92.5%.
Conclusion; Thus according to results of this study, it is revealed that TVS is a good diagnostic tool and can rule out the problem of post-menopausal bleeding and prevent the patients from invasive procedures.

Published
2020-03-25
Section
Original Articles