Is Hyosine Butylbromide a Good Choice for Shortening Labour Duration?

Abstract

Objective:  To find out the role of Hyoscine butyl bromide (HBB) in the form of buscupan in reducing the length of the active first stage of labour.

Methodology: A total of 124 pregnant women fulfilling inclusion criteria were included in the study. Group A received a stat dose of intravenous 20mg Hyoscine Butyl bromide (Buscopan), while Group B had 2ml of water for injection (placebo) at full cervical effacement and ≥5 cm of dilatation. Labour was monitored throughout by using partogram. The mean outcome was the duration of the active Ist stage of labour. Data was analysed using SPSS version 20. The duration of labour and the rate of cervical dilation were expressed as means+SDs). The difference between groups was compared using independent t-test for continuous data and chi square for categorical data. The p value of ≤0.05 was considered as significant.

Results: The mean duration of the active first stage of labour was 206.51 ±5.49 minutes in the Buscupan group as compared to 267±6.38 minutes in the placebo group (mean difference= 61.44 minutes) which is statistically significant (p<0.001). There was also a slight reduction in second stage duration in women receiving buscupan (p=0.016).

Conclusion: Buscopan is an effective and safe drug for shortening the active first stage of labor, with no negative effects on the mother or newborn.