Intrauterine Progesterone Versus Oral Progesterone in the Treatment of Dysfunctional Uterine Bleeding
Objective: To compare the effect of intrauterine progesterone with oral progesterone in treatment of DUB. Study Design: Randomized Control Trial.
Place and Duration: Outdoor & indoor patients in obstetrics & gynecology department Allied Hospital Faisalabad, from 1st Jan 2014 to first Jan 2015.
Methodology: Seventy-four (74) patients from outdoor and indoor with dysfunctional uterine bleeding fulfilling the inclusion and exclusion criteria were assessed for effect of both therapies. To each Group (A and B) 37 patients randomly allocated and then effects of both therapies were compared. All the variables of study were recorded and results were calculated.
Results: Decrease of menstrual blood loss was more in group A than group B assessed in the form of reduced number of pads used per day 59.4% in group A versus (vs) 32.43% in group B. Menstrual bleeding stopped 3 days earlier than usual 29.7% in group A vs 13.5% in group B. Clots were absent in 73% in group A vs 45.9% in group B. Improvement in Hemoglobin(Hb) was 59.46% in group A vs 16.22% in group B.
Conclusion: Intrauterine progesterone is more effective than oral progesterone in the treatment of DUB. Key Words: Dysfunctional uterine bleeding(DUB), Heavy menstrual bleeding (HMB). Menorrhagia, Intrauterine progesterone, Oral progesterone(OP), Intrauterine levonorgestrel releasing system (LNG- IUS).
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