Intrauterine Progesterone Versus Oral Progesterone in the Treatment of Dysfunctional Uterine Bleeding

  • Sarwat Ara Associate Professor, Gynecology & Obstetrics Department, PMC Allied Hospital, Faisalabad
  • Rashda Shahid Senior Registrar, Gynecology & Obstetrics Department, PMC Allied/DHQ Hospital, Faisalabad
  • Ahmad Khan Ex.House Officer, I.H.U, Faisalabad
Keywords: Intrauterine levonorgestrel releasing system, Dysfunctional uterine bleeding, Menorrhagia, Intrauterine progesterone


Objective: To compare the effect of  intrauterine progesterone with oral progesterone in treatment of DUB. Study Design: Randomized Control Trial.
Place and Duration: Outdoor & indoor patients in obstetrics & gynecology department Allied Hospital Faisalabad, from 1st Jan 2014 to first Jan 2015.
Methodology:  Seventy-four (74) patients from outdoor and indoor with dysfunctional uterine bleeding fulfilling the inclusion and exclusion criteria were assessed for effect of both therapies. To each Group (A and B) 37 patients randomly  allocated  and  then effects of both therapies were compared. All the variables of study were recorded and results were calculated.
Results: Decrease of menstrual blood loss was more in group A than group B assessed in the form of reduced number of pads used per day 59.4% in group A versus (vs) 32.43% in group B. Menstrual bleeding stopped 3 days earlier than usual 29.7% in group A vs 13.5% in group B. Clots were absent in 73% in group A vs 45.9% in group B. Improvement  in  Hemoglobin(Hb) was 59.46% in  group  A vs 16.22% in group B.
Conclusion: Intrauterine progesterone is more effective than oral progesterone in the treatment of DUB. Key Words: Dysfunctional uterine bleeding(DUB), Heavy menstrual bleeding (HMB). Menorrhagia, Intrauterine progesterone, Oral progesterone(OP), Intrauterine levonorgestrel releasing system (LNG- IUS). 

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